HotFlux by Corum | -Glenn Corp- an Azelis Company


Vanillyl butyl ether
Chemical Function: ,
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Not available (from Glenn) in the following state(s):
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HotFlux is a mild warming agent that rejuvenates hair growth and enhances microcirculation.

The functional group is called the vanillyl group; it plays the main role in inducing the warming sensation via the nervous system. The sensory neurons are activated through the binding of vanillyl group to its reception, named vanilloid receptor-1 (VR-1). The activated sensory neurons will release glutamate, APT, and a variety of neuropeptides as neurotransmitters from the synapse. The neurons eventually reach the central nervous system and launch a cascade of a warm sensation, which can also be similarly triggered by a temperature of ≧ 43°C.

It is recommended to add this ingredient at the last step in the formulation process.

Interested in learning more about HotFlux? Click Here to view the brochure!

Features & Benefits of HotFlux

  • Low Irritation
  • Long lasting warming sensation
  • Enhancing microcirculation
  • Preventing hair loss & Improving hair growth


  • Massage Cream/Oil
  • Warming Cream/Oil
  • Slimming Cream/Oil

Helps Rejuvenate Hair Growth By:

  • Imparting a relaxing warming sensation
    • sooth and reduce the feeling of stress -> decrease inflammation
  • Enhancing microcirculation
    • more nutrients delivered to the hair follicles
  • Preventing hair loss
    • reduce inflammatory cytokines such a IL-6 and IL-8
  • Improving hair growth
    • up-regulate hair growth factors such as IGF-1, VEGF, bFGF



Enhances the local blood cell flow. 0.3% of this cream can increase perfusion up to 30.24% and 66.4% for 0.5%


HotFlux cream with an average perfusion time of more than 30 minutes.




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Vanillyl butyl ether

    • INCI
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      Vanillyl butyl ether
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