Sytenol® A is the first natural alternative to retinol, offering comparable clinical performance without the irritation, dryness, or sensitivity often associated with traditional retinoids.

With a purity of ≥99%, it is both photochemically and hydrolytically stable, allowing for safe daytime use without photosensitivity concerns. Extensive studies show that Sytenol® A modulates retinoid-binding and metabolizing genes, significantly improves dermal and dermo-epidermal junction proteins, and stimulates Collagen I, III, and IV production for stronger, firmer skin. It also enhances hydration by upregulating hyaluronic acid and aquaporin 3 synthesis.

Highlights:

• As a plant-based compound, it offers a gentler alternative to synthetic retinol, with a lower risk of irritation.
• In a 12-week study, bakuchiol users reported up to 5 times less facial skin scaling and stinging than retinol users.
• The same study showed a 59% reduction in hyperpigmentation, compared to only a 44% reduction in the retinol group.
• Unlike some retinoids, it is photostable, i.e., it’s stable when exposed to light, making it suitable for daytime use.

In the years since the team at Sytheon, now part of Hallstar, introduced Sytenol® A Bakuchiol to the world, they have conducted rigorous research and published extensive data on its multiple benefit,s ensuring scientific precision, reliability, and proven safety.

Clinically, Sytenol® A delivers visible reduction in skin roughness, dryness, fine lines, and wrinkles, while improving tone, elasticity, firmness, radiance, and brightness — redefining what’s possible with natural skincare. Suggested use levels are 0.5 to 1%.

Sytheon limited was purchased in November 2024 and their line of products including this one is now available within the Hallstar Beauty portfolio.